Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0309387
PubChem CID
Molecular Formula
C6H16N6
Molecular Weight
172.236 g/mol
Synonyms/Alias
[arcaine; 1;4-Diguanidinobutane; Tetramethylenediguanide; 544-05-8; N;N-1;4-Butanediylbisguanidine; 2-[4-(diaminomethylideneamino)butyl]guanidine; 1;1-(butane-1;4-diyl)diguanidine; 1-(4-guanidinobutyl...
InChI Key
HGMDNMBBCKDWTQ-UHFFFAOYSA-N
InChI
InChI=1S/C6H16N6/c7-5(8)11-3-1-2-4-12-6(9)10/h1-4H2,(H4,7,8,11)(H4,9,10,12)
IUPAC Name
2-[4-(diaminomethylideneamino)butyl]guanidine
CAS Number
58-32-2

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

28 27 0 0 0 0 0 0 0 0999 V2000
-0.6978 -1.0575 -1.1953 C 0 0 0 0 0 0 0 0 0 0 0 0
0.5219 -0.9440 -0.2705 C 0 0 0 0 0 0 0 0 0 0 0 0
1.8237 -1.166...

Experimental Data

Activity Data

Target Ion Channel
Acid-sensing ion channel 3
Uniprot Accession Number
Function
Activator
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
pEC50:  3.5
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.2
Holding Potential
−60 mV mV
Temperature
23 ± 2 °C
Test Method
Patch-clamping
Test Species
CHO cell (Chinese hamster ovary cell)

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
12
Rotatable Bonds
5
logP
-1.6866
Complexity
50.5876
TPSA (Ų)
128.8
H-Bond Donors
4
H-Bond Acceptors
2
Ring Count
0
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